Russia, Britain, Sweden and Italy all reported their first cases, Rome declaring its own national emergency as it sought to reconstruct the itinerary of two infected Chinese tourists.

“Do not travel to China due to novel coronavirus first identified in Wuhan,” the U.S. State Department said, raising the warning for China to the same level as Afghanistan and Iraq.

Beijing, which has only just started to mend tattered trade ties with the United States, called that move “truly mean” given the World Health Organization (WHO) had commended its containment efforts and not recommended travel or trade curbs.

“The World Health Organization urged countries to avoid travel restrictions, but very soon after that, the United States did the opposite,” Chinese Foreign Ministry spokeswoman Hua Chunying said in a statement. “It’s truly mean.”

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Japan also advised citizens to put off non-urgent travel to China, while Bahrain recommended no travel to any country hit by the virus, and Iran urged a ban on all travelers from China.

Singapore, a major travel hub in Asia, stopped entry of passengers with a recent history of travel to China and also suspended visas for Chinese passport holders.

The ban extends to those just transiting Singapore.

With major fallout inevitable for the world’s No. 2 economy, global shares were heading for their biggest weekly losses since August on Friday, and oil and metals markets were showing even more brutal damage.

The outbreak could “reverberate globally”, Moody’s said.

In the latest impact to big name corporations, South Korea’s Hyundai Motor (005380.KS) said it planned to halt production of a sport utility vehicle this weekend to cope with a supply disruption caused by the outbreak. Sangyong Motor (003620.KS) said it would idle its plant in the South Korean city of Pyeongtaek from Feb. 4-12 for the same reason.

Home appliance maker Electrolux (ELUXb.ST) issued a similar warning. And French carmaker PSA Peugeot Citroen (PEUP.PA) said its three plants in Wuhan will remain closed until mid-February.

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